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What is the difference between industrial clean rooms and biological clean rooms?

What is the difference between industrial clean rooms and biological clean rooms?

A clean room is a closed and controlled area that controls parameters such as air quality, temperature, humidity, and pressure to ensure that the number of particles and active biological substances in the environment is maintained within a certain range. The work performed in clean rooms is of great significance to some special fields such as electronics manufacturing, pharmaceuticals, food processing, etc. In the application fields of clean rooms, industrial clean rooms and biological clean rooms are two common types. While they both strive to create a clean work environment, they differ in some key ways.

1. Industrial clean rooms are mainly used in industrial production and manufacturing processes to eliminate or control the impact of particulates on product quality. The focus of industrial clean rooms is to control and reduce contamination of products by dust, static electricity, chemicals, and other pollutants in the environment. Therefore, the design and layout of industrial clean rooms pay more attention to air filtration and airflow control systems to minimize the generation and spread of particles.

In contrast, biological clean rooms are mainly used in fields such as bioscience experiments, pharmaceutical research and development, and biomanufacturing. The main task of a biological clean room is to protect experimental samples, research objects, and products from external sources of contamination. Therefore, the focus of biological cleanrooms is to prevent microbial contamination and cross-contamination. In addition to air filtration and air flow control, biological cleanrooms also need to take other protective measures, such as the use of sterile techniques, regular disinfection, and wearing personal protective equipment, to ensure the reliability of experiments and the accuracy of results.

2. There are differences between industrial clean rooms and biological clean rooms in terms of air cleanliness requirements. Industrial clean rooms are usually divided into different levels of cleanliness according to the ISO 14644 standard, such as ISO 5, ISO 7, and ISO 9. An ISO Class 5 cleanroom requires no more than 0.1 microns of solid particles per cubic meter of air. Biological clean rooms focus on the control of microbial contamination and are usually divided into different levels according to the USP <797> standard, such as ISO 5, ISO 7, and ISO 8. ISO Class 5 biological clean rooms require that the number of viable bacteria per cubic meter of air does not exceed 1 CFU (colony count).

3. Industrial clean rooms and biological clean rooms also differ in equipment and layout. In industrial clean rooms, common equipment includes air filters, pressure difference control systems, static eliminators, etc. The biological clean room needs to add more equipment and protective measures, such as a sterile workbench, biological safety cabinet, and personnel access control system. In addition, biological cleanrooms also need to pay attention to cross-contamination issues between different laboratories, so equipment such as airlocks and eyewash stations are usually set up in different areas.

To summarize, there are significant differences between industrial cleanrooms and biological cleanrooms in terms of design, air cleanliness requirements, and equipment layout. Industrial clean rooms focus more on controlling particle contamination of products, while biological clean rooms focus more on preventing microbial contamination and cross-infection. For different application areas, choosing the appropriate clean room type is key to ensuring a clean working environment and protecting products and the reliability of experimental results. Bailun Purification provides professional purification equipment for clean rooms in various industries. The production types are diverse, including transfer windows, air showers, high-efficiency air supply outlets, negative pressure weighing rooms, 100-level laminar flow hoods, FFU laminar flow air supply units, clean Workbench, etc. These purification equipment can be customized to design and produce according to the clean room needs of different industries to ensure high-efficiency production and worker safety.