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How to maintain laminar flow hoods in the pharmaceutical industry

How to maintain laminar flow hoods in the pharmaceutical industry

In the pharmaceutical industry, the correct maintenance of laminar flow hoods is crucial, which is directly related to the quality of drugs and the cleanliness of the production environment. The following are the maintenance methods for laminar flow hoods in the pharmaceutical industry:
I. Daily maintenance
1. Cleaning work
- Clean the outer surface of the laminar flow hood regularly. You can use a clean cloth without fiber shedding and a special cleaner. Be careful to avoid scratching the surface of the equipment when wiping.
- Clean the air inlet and outlet of the laminar flow hood to prevent dust and debris from clogging and affecting air circulation and filtering effects. You can use a vacuum cleaner or compressed air for blowing, but be careful not to use too much pressure to avoid damaging the filter.
2. Check the filter
- Regularly check the high-efficiency filter of the laminar flow hood to observe whether its appearance is damaged, deformed, or has too much dust accumulation. If the filter is found to have problems, it should be replaced in time.
- Check the pressure differential gauge of the filter. When the pressure differential exceeds the specified value, it also indicates that the filter needs to be replaced. Generally speaking, the replacement cycle of the high-efficiency filter depends on the use environment and frequency, usually 6 months to 1 year.
3. Check the fan
- Listen to the sound of the fan running to see if it is normal. If there is abnormal noise or vibration, check whether the bearings, impellers and other parts of the fan are damaged or loose.
- Check whether the speed of the fan is stable. You can use a tachometer to measure it. If the speed is unstable, it may be a motor failure or a speed regulator problem, which needs to be repaired or replaced in time.
4. Check the electrical system
- Regularly check the electrical system of the laminar flow hood, including whether the power cord, switch, socket, etc. are normal, loose, damaged, or leaking.
- Check whether the indicator lights and display screen on the control panel are normal. If there is a fault, it should be repaired in time.
II. Regular maintenance
1. Comprehensive cleaning
- Clean the laminar flow hood thoroughly every once in a while (generally 3 to 6 months). In addition to the parts that are cleaned daily, it should also include the internal air duct, static pressure box, and other parts. You can use professional cleaning tools and cleaning agents to ensure thorough cleaning.
2. Filter replacement
- Replace the high-efficiency filter according to the prescribed replacement cycle, and properly dispose of the replaced filter to avoid pollution to the environment.
- When replacing the filter, pay attention to the operating specifications to ensure that the filter is installed correctly and sealed well.
3. Fan maintenance
- Regularly maintain the fan, including cleaning the bearings, adding lubricating oil, checking the impeller balance, etc. If the fan fails, it should be repaired or replaced in time.
4. Calibration and testing
- Regularly calibrate and test the wind speed, pressure difference, cleanliness, and other parameters of the laminar flow hood to ensure that the performance of the equipment meets the requirements. You can entrust a professional testing agency to conduct the test, or you can use your testing equipment for self-test.
- If the test results do not meet the requirements, you should find the cause and make corrections in time until the equipment performance meets the standard.
III. Precautions
1. Maintenance personnel should undergo professional training, be familiar with the structure, performance, and maintenance methods of the laminar flow hood, and perform maintenance in strict accordance with the operating procedures.
2. During the maintenance process, pay attention to safety to avoid accidents such as electric shock and mechanical injuries. Especially when performing electrical system maintenance and fan maintenance, cut off the power supply first and take corresponding safety measures.
3. The tools and cleaning agents used for maintenance should meet the requirements of the pharmaceutical industry and should not cause pollution to equipment and drugs.
4. The replaced filters and other waste should be handled by regulations and should not be discarded at will.
5. Regularly organize and archive maintenance records for easy traceability and management.
In short, the maintenance of laminar flow hoods in the pharmaceutical industry needs to be carried out strictly by the specifications to ensure the stable performance and cleanliness of the equipment and provide reliable protection for drug production.