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Which industries are clean benches suitable for?

Which industries are clean benches suitable for?

Clean benches are widely used in the following industries: 1. Medical industry 1. Clinical testing In the laboratory of the hospital, the clean bench provides a clean operating environment for the testing of samples such as blood, urine, and feces. For example, when conducting microbiological tests, such as bacterial culture and drug sensitivity tests, the clean bench can prevent contamination by external bacteria and ensure the accuracy of the test results. Even a small amount of external bacteria mixed into the sample may lead to the detection of the wrong bacterial species or wrong drug sensitivity results, thereby affecting the patient's diagnosis and treatment. 2. Surgical instrument processing The hospital's disinfection supply center needs to clean, disinfect, and package surgical instruments. The clean bench can be used for the inspection and packaging of some precision surgical instruments. This process, can prevent the instruments from being contaminated by dust and microorganisms in the air again, ensure the sterility of the instruments, and provide protection for the safety of the operation. 3. Drug production and preparation The hospital's intravenous drug preparation center (PIVAS) must operate on a clean bench when preparing intravenous infusions such as cytotoxic drugs and antibiotics. Clean benches can prevent drugs from being contaminated and ensure the quality and safety of drugs. For example, when preparing chemotherapy drugs, it is necessary to avoid external impurities from mixing into the drugs and reduce the risk of adverse reactions in patients due to drug contamination. At the same time, in the sterile drug production workshops of pharmaceutical companies, such as the production of injectable vaccines, biological agents, and other drugs, clean benches are also indispensable equipment for key processes such as drug filling and freeze-drying.
4. Tissue culture and transplantation
In the field of tissue engineering and regenerative medicine, clean benches are used for cell culture and preparation of tissue engineering scaffolds. For example, when culturing skin tissue for transplantation of burn patients, the sterile environment provided by the clean bench can prevent cells from being contaminated and ensure that the cultured tissue can grow and function normally. For the preservation and processing of organs in organ transplantation surgery, the clean bench can also provide a relatively clean environment to reduce the risk of infection.
2. Biotechnology industry
1. Genetic engineering
In experimental operations such as gene cloning and gene editing, clean benches are crucial equipment. For example, when using CRISPR-Cas9 technology for gene editing, cells need to be transfected in a clean bench. Because this process involves introducing gene editing tools (such as vectors containing Cas9 protein and sgRNA) into cells, if interfered with by external microorganisms or impurities, it may lead to a decrease in transfection efficiency and even affecting the accuracy of gene editing, thus failing to obtain the expected gene-edited cells.
2. Cell Engineering
For operations such as cell culture, fusion, and monoclonal screening, the clean bench is the basic operating platform. For example, in the production of monoclonal antibodies, it is first necessary to fuse immunized animal spleen cells and myeloma cells in the clean bench, and then screen hybridoma cells that can produce specific antibodies in the clean environment. Without the sterile environment provided by the clean bench, cells are easily contaminated and die, resulting in the failure of the entire production process.
3. Microbial Fermentation
In the process of microbial fermentation to produce bioactive substances (such as antibiotics, enzymes, amino acids, etc.), the clean bench can be used for the inoculation and initial culture of microbial strains. In the inoculation stage, ensuring that the strains are not contaminated by miscellaneous bacteria is the key to successful fermentation. For example, in the fermentation process of penicillin production, the Penicillium species must be inoculated into the fermentation medium in the clean bench, otherwise, other bacteria may multiply in large numbers at the beginning of the fermentation, consume the nutrients in the medium, inhibit the growth of Penicillium, and may produce harmful metabolites, affecting the yield and quality of penicillin.
III. Electronics Industry
1. Semiconductor Manufacturing
In the manufacturing process of semiconductor chips, the clean bench is used for high-precision processes such as chip lithography and etching. Chip manufacturing requires extremely high environmental cleanliness, because even tiny dust particles falling on the surface of the chip may cause the chip to short-circuit or degrade performance. For example, in the lithography process, the clean bench can prevent dust from interfering with the accuracy of the lithography pattern, ensuring that the circuit pattern on the chip can be accurately manufactured according to the design requirements, thereby ensuring the quality and performance of the chip.
2. Assembly of Electronic Components
When assembling high-precision electronic components (such as micro-electromechanical systems (MEMS), sensors, etc.), the clean bench can prevent dust, static electricity, and other factors from damaging the components. For example, when assembling an acceleration sensor, the clean bench can reduce dust adsorption on the sensitive elements of the sensor, avoid sensor output signal errors caused by dust, and improve product reliability and accuracy.
4. Food Industry
1. Food Microbiological Testing
In the quality control laboratory of a food company, the clean bench is used to detect microbial indicators in food, such as total colony count, coliform group, pathogenic bacteria, etc. During the detection process, it can prevent interference from external microorganisms to ensure that the test results truly reflect the microbial contamination in the food. For example, when testing the bacterial content in milk, the clean bench can ensure that no external bacteria will be mixed into the sample during the detection process, to accurately determine whether the milk meets the hygiene standards.
2. Aseptic Food Packaging
For some aseptic foods that need to be stored for a long time (such as canned foods, aseptically packaged beverages, etc.), the clean bench is used in the packaging of food. In this process, ensuring the aseptic state of the packaging environment can extend the shelf life of the food. For example, in the production process of aseptically packaged juice, filling and sealing the juice in a clean bench can prevent bacteria, mold, and other microorganisms from entering the packaging, ensuring the quality and safety of the juice.